Related articles have been published in a supplement to BMC Bioinformatics.
An integrative framework for the identification of double minute chromosomes using next generation sequencing data
Double minute chromosomes are circular fragments of DNA whose presence is associated with the onset of certain cancers. Double minutes are lethal, as they are highly amplified and typically contain oncogenes. ...
Citation: BMC Genetics 2015 16(Suppl 2):S1