Molecular characterization and phylogenetic analysis of the first Corynebacterium rouxii strains isolated in Brazil: a recent member of Corynebacterium diphtheriae complex

Table 4 Description of the mutations found in the penicillin-binding proteins

Strains	Penicillin-binding proteins (PBPs)
Strains	PBP1a	PBP1b	PBP2a	PBP2b	PBP2c	PBP4	PBP4b
70,862 and 70,863	416: S➜P 430: S ➜G 669: V ➜A 699: A ➜V	699: I ➜V	181: S ➜A	69: V ➜A	196: H ➜Y 260: P ➜L	no mutations	34: V ➜A 362: T ➜S

The numbers before the amino acid abbreviations indicate the site where the mutations occurred
Amino acids abbreviations: S serine, P proline, G glycine, V valine, A alanine, I isoleucine, H histidine, Y tyrosine, L leucine, T threonine
Gene location in the type strain FRC0190 with the respective locus_tag in parentheses: PBP1a (CIP100161_RS11445); PBP1b (CIP100161_RS01510); PBP2a (CIP100161_RS00415); PBP2b (CIP100161_RS08085); PBP2c (CIP100161_RS07615); PBP4 (CIP100161_RS10180); and PBP4b (CIP100161_RS03210)

ISSN: 2730-6844