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Fig. 1 | BMC Genomic Data

Fig. 1

From: 3-D chromatin conformation, accessibility, and gene expression profiling of triple-negative breast cancer

Fig. 1

Study design for the generation of insulator element proficient and deficient TNBC cell line models. TNBC cell lines MDA-MB-231 and MDA-MB-436 were considered eligible for the study. They were transiently transfected with PX458 using Lipofectamine 3000. 48 h after transfection, GFP-positive cells were sorted. After model generation functional experiments and multi-omic assays, including ATAC-seq, Hi-C, and RNA-seq were performed

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