Table 3 SNPs associated with the multivariate phenotype of ACL rupture and coat color in the Labrador Retriever using Bayesian GWAS with mvBIMBAM [36]
Chr | Position | Number of SNPs | BF(mult) | BF(ACLR) | BF(color) | PPE(ACLR) | PPE(color) | Interpretation of association | Gene |
|---|---|---|---|---|---|---|---|---|---|
2 | 71,101,534–71,129,159 | 4 | 3.39–3.76 | -0.25-(-0.19) | 3.61–4.04 | 0.41 | 1.00 | color | Non-coding |
3 | 6,904,814 | 1 | 3.12 | -0.22 | 3.51 | 0.49 | 1.00 | color | Non-coding |
5 | 63,697,949 | 1 | 31.05 | -0.32 | 31.30 | 0.34 | 1.00 | color | TCF25 |
5 | 64,529,952 | 1 | 22.09 | -0.17 | 22.55 | 0.51 | 1.00 | color | TRAPPC2L |
5 | 65,740,974 | 1 | 21.88 | -0.24 | 22.30 | 0.46 | 1.00 | color | Non-coding |
5 | 62,868,802 | 1 | 20.84 | -0.14 | 20.43 | 0.29 | 1.00 | color | SLC25A33 |
5 | 65,726,354 | 1 | 20.24 | -0.23 | 20.67 | 0.47 | 1.00 | color | FBXO31 |
5 | 64,048,349 | 2 | 17.07–17.34 | -0.29 | 17.33–17.59 | 0.35 | 1.00 | color | ANKRD11 |
5 | 63,957,203 | 1 | 14.39 | -0.08 | 14.86 | 0.56 | 1.00 | color | CPNE7 |
5 | 63,097,333 | 1 | 12.20 | -0.29 | 12.56 | 0.41 | 1.00 | color | CTNNBIP1 |
5 | 63,988,836 | 1 | 11.13 | -0.20 | 11.55 | 0.49 | 1.00 | color | SPG7 |
7 | 32,703,446 | 1 | 4.52 | -0.04 | 4.89 | 0.57 | 1.00 | color | RGS7 |
10 | 23,299,673 | 1 | 3.04 | -0.12 | 3.26 | 0.46 | 1.00 | color | FAM109B |
10 | 35,494,733 | 1 | 3.03 | -0.03 | 3.10 | 0.51 | 1.00 | color | SULT1C4 |
16 | 26,472,996–26,477,692 | 3 | 3.27–3.91 | -0.25-(-0.14) | 3.43–4.17 | 0.40–0.43 | 1.00 | color | ADAM9 |
23 | 34,304,346–34,308,607 | 3 | 3.08–3.11 | 3.42–3.46 | -0.23-(-0.22) | 1.00 | 0.45 | ACLR | DZIP1L |
24 | 40,095,242 | 1 | 3.03 | 0.81 | 2.10 | 0.91 | 1.00 | color and ACLR | Non-coding |
26 | 27,293,677–27,476,357 | 7 | 3.14–4.36 | -0.25-(-0.04) | 3.46–4.61 | 0.40–0.58 | 1.00 | color | Non-coding |
26 | 27,898,308–27,910,578 | 3 | 3.09–3.20 | -0.26-(-0.25) | 3.43–3.55 | 0.42–0.44 | 1.00 | color | BCR |
26 | 27,762,329 | 1 | 3.02 | -0.22 | 3.26 | 0.42 | 1.00 | color | RTDR1 |