Fig. 1From: Identification of genetic variants associated with anterior cruciate ligament rupture and AKC standard coat color in the Labrador RetrieverManhattan plot of mvBIMBAM and GEMMA results for the multivariate phenotype of anterior cruciate ligament rupture and coat color. (A) Data for the mvBIMBAM analysis is shown as log10Bayes factors (BF) and (B) GEMMA data are displayed as log10P with the associated QQ plot of expected and observed P-values for GEMMA analysis to assess population stratification. SNPs on chromosome 5 displayed the most significant associations with the multivariate phenotype. There were also SNPs on chromosomes 2, 3, 7, 10, 16, 23, 24, 26, and 30 that showed significant association. Genome-wide significance cut-off is shown at Log10(BF) = 3.0 and -Log10(P) = 6.22. Lamda = 2.033Back to article page