Exploring the association between COVID-19 and male genital cancer risk in European population: evidence from mendelian randomization analysis

Table 1 Selected genetic variants for COVID-19 based on the GWAS significance

	SNP	EA	OA	beta.E	beta.O	eaf.E	chr	pos	se.O	No.O	pval.O	se.E	pval.E	No.E
1	rs13050728	C	T	-0.168	0.000	0.653	21	34,615,210	0.000	361,194	0.946	0.020	7.44E-17	1,887,658
2	rs2109069	A	G	0.151	0.000	0.323	19	4,719,443	0.000	361,194	0.342	0.020	2.94E-14	1,887,658
3	rs2660	A	G	0.116	0.000	0.690	12	113,357,442	0.000	361,194	0.805	0.019	2.00E-09	1,887,658
4	rs35081325	T	A	0.488	-0.001	0.081	3	45,889,921	0.001	361,194	0.401	0.032	3.68E-54	1,887,658
5	rs505922	C	T	0.112	0.000	0.350	9	136,149,229	0.000	361,194	0.149	0.019	4.42E-09	1,887,658

The present study employs a GWAS approach, wherein variants demonstrating statistical significance at a level of P ≤ 5 × 10^8 are considered. Furthermore, a linkage disequilibrium threshold of R^2 < 0.1 is utilized to assess the extent of correlation between identified variants. EA Effect allele, OA Other alleles, E Exposure, O Outcome, No Numbers of sample size

ISSN: 2730-6844