Table 1 Number of significantly associated genes with negative and positive effect sizes
From: Gene-based burden scores identify rare variant associations for 28 blood biomarkers
Biomarker | Negative effect | Positive effect |
|---|---|---|
Alanine aminotransferase | 1 | 1 |
Albumin | 4 | 2 |
Alkaline phosphatase | 5 | 6 |
Apolipoprotein A | 7 | 9 |
Apolipoprotein Ba | 6 | 3 |
Aspartate aminotransferase | 1 | 8 |
Cholesterola | 8 | 7 |
Creatinine | 1 | 27 |
Cystatin C | 2 | 9 |
Direct bilirubin | 3 | 10 |
Gamma glutamyltransferase | 3 | 9 |
Glucose | 1 | 2 |
Glycated haemoglobin (HbA1c) | 3 | 8 |
HDL cholesterol | 8 | 9 |
IGF1 | 4 | 1 |
LDL directa | 7 | 4 |
Lipoprotein A | 2 | 1 |
Phosphate | 4 | 3 |
SHBG | 4 | 1 |
Testosterone | 1 | 1 |
Total bilirubin | 7 | 7 |
Total protein | 5 | 1 |
Triglycerides | 8 | 5 |
Urate | 3 | 3 |
Vitamin D | 1 | 5 |