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Fig. 4 | BMC Genomic Data

Fig. 4

From: Comprehensive analysis of m6A regulators and relationship with tumor microenvironment, immunotherapy strategies in colorectal adenocarcinoma

Fig. 4

Construction of the m6Ascore and evaluation of the relationship between m6Ascore and clinical characteristics of COAD patients. A K-M curve of high- and low-m6Ascore groups. The patients in high-m6Ascore group had better outcome than those in low-m6Ascore group (P < 0.001). B K-M curve of an independent validation cohort (P = 0.007). C The ROC curve of the m6Ascore for predicting prognosis of COAD patients was plotted and the AUC was 0.775. D The AUC of the m6Ascore in validation cohort was 0.701. E The difference of m6Ascore was compared in the two m6A clusters. The m6Ascore was higher in cluster A (P = 6.9e-11). F The m6Ascore was correlated with patient’s survival status (P = 2.3e-05), clinical stage (P = 4.5e-06), T stage (P = 0.00017), N stage (P = 9.8e-06) and M stage (P = 8.6e-05). However, there was no significant correlation between m6Ascore and age (P = 0.79), gender (P = 0.26)

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BMC Genomic Data

ISSN: 2730-6844

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