The shared genetic architecture of smoking behaviours and psychiatric disorders: evidence from a population-based longitudinal study in England

Table 3 Associations between polygenic scores and heaviness of cigarette smoking among older adults from the general population in the UK

Polygenic scores	Heaviness of cigarettes smoking
Polygenic scores	OR	SE	95%CI	p
SZ-PGS	1.01	0.05	0.91–1.12	0.776
BD-PGS	1.00	0.05	0.90–1.12	0.913
MDD-PGS	1.11	0.05	1.00-1.24	0.028
IQ-PGS	0.97	0.05	0.88–1.07	0.501

SZ-PGS, polygenic score for schizophrenia; BD-PGS, polygenic score for bipolar disorder; MDD-PGS, polygenic score for major depressive disorder; IQ-PGS, polygenic score for intelligence; OR, odds ratio; SE, standard error; CI, confidence intervals

ISSN: 2730-6844