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Table 2 Associations between polygenic scores and likelihood to initiate cigarette smoking among older adults from the general population in the UK

From: The shared genetic architecture of smoking behaviours and psychiatric disorders: evidence from a population-based longitudinal study in England

Polygenic scores

  

Smoking initiation

 

OR

SE

95%CI

p

SZ-PGS

 

1.01

0.03

0.95–1.06

0.817

BD-PGS

 

1.00

0.03

0.94–1.05

0.888

MDD-PGS

 

0.99

0.03

0.94–1.05

0.835

IQ-PGS

 

1.00

0.03

0.95–1.06

0.895

  1. SZ-PGS, polygenic score for schizophrenia; BD-PGS, polygenic score for bipolar disorder; MDD-PGS, polygenic score for major depressive disorder; IQ-PGS, polygenic score for intelligence; OR, odds ratio’ SE, standard error; CI, confidence intervals