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Table 2 MC active components that may have effects on selected core proteins

From: Mechanisms of magnoliae cortex on treating sarcopenia explored by GEO gene sequencing data combined with network pharmacology and molecular docking

Molecule Name

Gene symbol

Protein name

PDB Entry

Protein crystal structure

Honokiol, Magnolol

AKT1

RAC-alpha serine/

threonine-protein kinase

1UNQ

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Honokiol, Magnolol

EGFR

Epidermal growth factor receptor

3P0Y

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Honokiol, Magnolol

INS

Insulin

1EV3

Obovatol

PIK3CA

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

5FI4