Identifying rare variants for quantitative traits in extreme samples of population via Kullback-Leibler distance

BMC Genomic Data

Table 2 The power of the QTL fine mapping for three LD measures by use of five-point moving average

Sample-selection threshold values	Power of the QTL fine mapping
	Recessive model			Additive model			Dominant model
	h² = 0.01	h² = 0.05	h² = 0.10	h² = 0.01	h² = 0.05	h² = 0.10	h² = 0.01	h² = 0.05	h² = 0.10
20%
l_KL	0.39	0.50	0.58	0.44	0.53	0.62	0.52	0.59	0.70
l	0.40	0.49	0.59	0.45	0.53	0.62	0.51	0.60	0.70
p_excess	0.29	0.36	0.47	0.36	0.47	0.58	0.41	0.52	0.61
10%
l_KL	0.49	0.59	0.66	0.52	0.64	0.70	0.62	0.69	0.80
l	0.50	0.59	0.67	0.53	0.63	0.71	0.61	0.68	0.80
p_excess	0.37	0.51	0.56	0.44	0.52	0.63	0.55	0.60	0.68
5%
l_KL	0.56	0.64	0.71	0.61	0.67	0.77	0.67	0.75	0.83
l	0.56	0.64	0.71	0.61	0.67	0.77	0.67	0.75	0.83
p_excess	0.41	0.55	0.63	0.48	0.51	0.65	0.59	0.68	0.72

Note: The MAF of the causal variant is 0.01(P_a = 0.01). The sample size is 1500 (2 N = 1500)

ISSN: 2730-6844