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Fig. 1 | BMC Genomic Data

Fig. 1

From: The choice of negative control antisense oligonucleotides dramatically impacts downstream analysis depending on the cellular background

Fig. 1

Overview of the experimental procedure. (a) Schematic representation of the experimental workflow. LECs and BECs were subjected to ASO-mediated knockdown (ASOKD) followed by Cap Analysis of Gene Expression (CAGE-Seq). Only samples with a knockdown efficiency higher than 50% in both replicates were subjected to CAGE-Seq. (b) Bioinformatic pipeline highlighting the quality control steps prior to the transcriptome profiling after lncRNA candidate knockdowns

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